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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDAC1
All Species:
42.12
Human Site:
T165
Identified Species:
71.28
UniProt:
P21796
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21796
NP_003365.1
283
30773
T165
E
T
A
K
S
R
V
T
Q
S
N
F
A
V
G
Chimpanzee
Pan troglodytes
XP_001151901
283
30732
T165
E
I
A
K
S
R
V
T
Q
S
N
F
A
V
G
Rhesus Macaque
Macaca mulatta
XP_001107652
283
30703
T165
E
T
A
K
S
R
V
T
Q
S
N
F
A
V
G
Dog
Lupus familis
XP_536597
256
28121
Q154
E
G
W
L
A
G
Y
Q
V
N
F
E
T
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60932
296
32333
T178
E
T
S
K
S
R
V
T
Q
S
N
F
A
V
G
Rat
Rattus norvegicus
Q9Z2L0
283
30737
T165
E
T
S
K
S
R
V
T
Q
S
N
F
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510394
343
37536
T178
E
T
T
K
S
R
V
T
Q
S
N
F
A
V
G
Chicken
Gallus gallus
NP_001029041
283
30688
T165
E
T
A
K
S
R
V
T
Q
S
N
F
A
V
G
Frog
Xenopus laevis
P81004
282
30052
T164
D
S
A
K
S
K
L
T
K
N
N
F
A
V
G
Zebra Danio
Brachydanio rerio
NP_001001404
283
30608
T165
E
A
G
R
N
R
I
T
Q
S
N
F
A
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94920
282
30532
T164
D
T
Q
Q
S
K
L
T
T
N
N
F
A
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21752
283
29942
A165
D
S
S
S
N
K
L
A
A
T
S
L
A
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04840
283
30410
S163
D
I
S
A
G
S
I
S
R
Y
A
M
A
L
S
Red Bread Mold
Neurospora crassa
P07144
283
29981
Y165
Q
K
A
A
I
T
G
Y
S
A
A
V
G
Y
H
Conservation
Percent
Protein Identity:
100
98.9
99.2
86.2
N.A.
94.2
98.5
N.A.
72.3
95.4
75.6
85.5
N.A.
58.2
N.A.
40.6
N.A.
Protein Similarity:
100
98.9
99.6
87.2
N.A.
95.2
99.6
N.A.
77.2
98.2
91.8
93.6
N.A.
75.9
N.A.
60.4
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
93.3
93.3
N.A.
93.3
100
60
66.6
N.A.
46.6
N.A.
13.3
N.A.
P-Site Similarity:
100
93.3
100
20
N.A.
100
100
N.A.
93.3
100
100
86.6
N.A.
86.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
31.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47
51.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
43
15
8
0
0
8
8
8
15
0
86
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
65
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
72
0
8
0
% F
% Gly:
0
8
8
0
8
8
8
0
0
0
0
0
8
0
79
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
15
0
0
8
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
58
0
22
0
0
8
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
0
0
22
0
0
0
0
8
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
22
72
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
0
8
58
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
58
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
15
29
8
65
8
0
8
8
58
8
0
0
0
8
% S
% Thr:
0
50
8
0
0
8
0
72
8
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
50
0
8
0
0
8
0
65
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _